題庫總數:15
是非題:0
選擇題:15 (A:5、B:0、C:1、D:9)
多選題:0
roddayeye整理
Q   關於多重抗藥性菌種院內感染之影響 ,下列何者正確?
    1.延長住院日數,造成殘疾、失去生命
    2.關閉病房、院譽受損、負法律責任
    3.增加工作量,增加感染之危險性
v   4.以上皆是 ||
     
Q   關於CRE(carbapenem-Resistant enterobacteriaceae)的Identification,下列何者有誤?
v   1.Clinical Laboratory and Standards Institute (CLSI) 為了偵測carbapenemase 的存在,已將MIC Breakpoints for Carbapenems提高
    2.Identification of E. coli or K. pneumoniae with overt resistance to any of the carbapenems should raise suspicion that it may be harboring a carbapenemase enzyme.
    3.臺灣的CDC有做CRE的抗藥性檢測
    4.NDM-1腸道菌感染症是法定傳染病 ||
     
Q   Infection Control for CRE (carbapenem-resistant enterobacteriaceae) ,下列何者有誤?
v   1.Hospitalized patients infected or colonized with carbapenemase-producing bacteria should be placed on airborn precautions
    2.Hand hygiene
    3.Antimicrobial stewardship
    4.Screening high-risk patients to detect rectal colonization. ||
     
Q   關於 Antimicrobial Therapy for CRE (carbapenem-resistant enterobacteriaceae)
    1.The optimal treatment of infection due to carbapenemase-producing organisms is uncertain
    2.CRE 會 confers resistance to all penicillins, cephalosporins, and carbapenems
v   3.For severe infections, monotherapy 較combination antimicrobial therapy with two or more agents 效果 為佳
    4.Emergence of resistance during monotherapy ||
     
Q   CRE(carbapenem-Resistantenterobacteriaceae)的transmission,下列何者有誤?
    1.Enterobacteriaceae,which harbor carbopenem-encoding genes,can spread from person to person
    2.Cross-infection within &outside of health system
    3.Health workers 的手也是主要傳播媒介
v   4.CRE因帶有mobile genetic elements,不會wide spread transmission to other isolates & genera of bacteria ||
     
Q   關于NDM(New Delhi metallo-β-lactamase)何者不正確?
v   1.Genetic element為chromosome
    2.Medical tourism 造成全球的擴散
    3.Widespread nonprescription use of antibiotics in India造成huge selection pressure
    4.Most common in E coli ||
     
Q   細菌對carbapenem有抗藥性的機制,下列何者不是?
    1.Loss of porins
    2.β-lactamase
    3.Overexpression of efflux pump
v   4.Target mutations ||
     
Q   下列何者carbapenemase在USA最常見
v   1.KPC (Klebsiella pneumoniae carbapenemase)
    2.NDM (New Delhi metallo-β-lactamase)
    3.Oxacillinase
    4.Amp C-like ||
     
Q   關於CRE(carbapenem-resistant enterobacteriaceae)的臨床表現,下列何者有誤?
    1.Asymptomatic colonization
    2.Outbreaks due to hospital-based clonal spread
    3.Central venous catheter infections.
v   4.以上皆非 ||
     
Q   下列何種情況 應考慮對病人應進行CRE (carbapenem-resistant enterobacteriaceae)主動篩檢?
    1.經調查後確定院內高風險區域
    2.於48小時內來自高風險區域(如:長照機構或已證實有CRE院內群突發醫院)之入院病人。
    3.病人須移轉至院內高風險區域(如:ICU)時。
v   4.以上皆是
     
Q   關於預防多重抗藥性菌種在病房傳播,下列何者有誤?
v   1.病人在單位間互轉,不用先告知是否為多重抗藥性菌種
    2.優先考慮將多重抗藥性菌種病人安置在單人病房
    3.將帶有相同多重抗藥性微生物的病人,集中照護
    4.不建議將帶有多重抗藥性菌種病人安置於高傳染風險病人旁 ||
     
Q   關於多重抗藥性菌種發生的經過 ,下列何者正確?
    1.在自然界中,原本就有抗藥性菌種存在
    2.使用抗生素 ,除了殺死病菌, 也會破壞體內正常的菌種, 而使抗藥性菌種有機會增長.
    3.抗藥性菌種會將抗藥性基因傳播給其他非抗藥性菌種
v   4.以上皆是 ||
     
Q   關於多重抗藥性菌種的院內感染管制措施 ,下列何者不正確?
    1.Hand hygiene
    2.Standard and contact precautions (e.g., gowns, gloves)
    3.Cohorting of patients and staff,
v   4.以上皆不正確 ||
     
Q   關于KPC(Klebsiella pneumoniae carbapenemase),何者有誤?
    1.Higher incidence in long-term care facilities than in acute care hospitals in U.S.A
    2.會造成hospital outbreak
    3.Transmissible plasmids
v   4.Can not transmitted from klebsiella to other genera ||
     
Q   Factors of antibiotic resistance,包括
    1.Aging population
    2.Chronic disease
    3.Invasive medical treatment
v   4.以上皆是 ||

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